Annihilation of the Wicked is the fourth studio album by American technical death metal band Nile. The album was released in Europe on May 23, 2005, by Relapse Records, and on May 24, 2005 in North America. This is the first Nile album to feature George Kollias on drums, replacing Tony Laureano. This album marks Nile's last record released by Relapse. The liner notes detail the theme and writing/recording process of each song. A music video for "Sacrifice Unto Sebek" was produced. It is also the first Nile album produced by Neil Kernon.